4th Edition Major Clans
The discipline marked with the asterisk (*) is generally unique to that clan and their sub-clans. It can be learned with diablorie.

Daeva (Succubi)
-Disciplines: Celerity, Majesty*, Vigor
-Weakness: Must have a vice worth at least -10 points.
-Bloodlines: Duchagne, Toreador, Xiao.

Gangrel
-Disciplines: Animalism, Fortitude, Protean*
-Weakness: Beastial Attributes [-1]
-Bloodlines: Anavashra, Anubi, Bruja, Matasuntha, Taifa.

Mekhet
-Disciplines: Auspex*, Celerity, Obfuscate
-Weakness: Double damage from sunlight and fire [-30]
-Bloodlines: Agonistes, Mnemosyne, Morbus, Norvegi, Sangiovanni.

Nosferatu
-Disciplines: Nightmare*, Obfuscaste, Vigor
-Weakness: Any -2 reaction or greater
-Bloodlines: Acteius, Baddacelli, Noctuku, Yagnatia, Burakumin.

Ventrue
-Disciplines: Animalism, Dominate*, Fortitude
-Weakness: Paranoia, greed, or self-important delusions worth at least -10 points.
-Bloodlines: Malkovian.

4th Edition Bloodlines (Sub-clans)
These clans can be chosen but require an unusual background to represent access to four disciplines.

Brujah
-Parent Clan: Gangrel
-Disciplines: Animalism, Fortitude, Protean, Vigor (Potence)
-Weakness: Must start with Self-Control -3, may never increase above Path.

Burakumin
-Parent Clan: Nosferatu
-Disciplines: Getsumei (not done), Nightmare, Obfuscate, Vigor (Potence).
-Weakness: Limited to status 2 or less (any type) [-1], Decaying appearance (-2 or worse), Unable to hide vampire features [-1]

Malkovians
-Parent Clan: Ventrue
-Disciplines: Auspex, Dominate, Fortitude, Obfuscate.
-Weakness: Must have at least a -10 point mental problem.

Morbus
-Parent Clan: Mekhet
-Disciplines: Auspex, Cachexy (not done), Celerity, Obfuscate.
-Weakness: May only feed from diseased or terminally ill [-15]. Often a carrier for disease [-1].

Toreador
-Parent Clan: Daeva
-Disciplines: Celerity, Dominate, Majesty, Vigor
-Weakness: Same as 3rd edition Toreador.

Vampire Factions
Certain faction will give access to an additional discipline.

The Carthian Movement seeks to reconcile Kindred society with modern governmental structures and social systems.

The Circle of the Crone venerates a variety of female figures as an amalgamated creator of vampires, the Mother of all Monsters. Members of this group may learn Cruac.

The Invictus is the aristocracy of the night.

The Lancea Sanctum seeks to influence Kindred society with the strictures of Longinus, whoc is believe to have been turned into one of the Damned by the very blood of Christ. Members of this group may learn Theban Sorcery.

Ordo Dracul commands rituals and mystical knowledge that allows the Kindred to transcend their vampire states. Members of this group may learn Coils of the Dragon (Special Discipline).

The Unaligned

Belial's Brood